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Mfsd2aem1(cre/ERT2)Bzsh - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Mfsd2aem1(cre/ERT2)Bzsh
MFSD2 lysolipid transporter A, lysophospholipid; endonuclease-mediated mutation 1, Bin Zhou 		Driver: Mfsd2a
Type: Endonuclease-mediated (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Mfsd2a-CreER
Molecular description: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A complementary DNA encoding Cre recombinase fused with a mutant form of the ESR hormone-binding domain (CreERT2) was inserted in frame with the translational start codon of the Mfsd2a gene.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Mfsd2aem1(cre/ERT2)Bzsh activity also observed in:
alimentary system, head, liver & biliary system, nervous system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:242859 Fig. Sup 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory