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Tg(Sox10-ERT2/cre/ERT2)17Sor - Mesenchyme
Recombinase Activity Detail
Allele Information
Allele:
Tg(Sox10-ERT2/cre/ERT2)17Sor
transgene insertion 17, Philippe Soriano 		Driver: Sox10
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: SECE17, Sox10ERT2CreERT2
Molecular description: The Multiple Species Conserved Sequence 4 (MCS 4) distal enhancer with a c-Fos minimal promoter drives neural crest cell and derivatives-specific expression of an inducible cre recombinase gene flanked by two modified estrogen receptors (ERT2/cre/ERT2) followed by a rabbit globin polyadenylation sequence. Two lines were generated with line 17 selected as the representative line.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Sox10-ERT2/cre/ERT2)17Sor activity also observed in:
Tissue Information
Mesenchyme Other recombinase alleles with activity in Mesenchyme tissues:
Images
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J:226186 Fig. 1 J:226186 Fig. 2 J:226186 Fig. 3 J:226186 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory