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Tg(Arc-cre/ERT2)MRhn - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Arc-cre/ERT2)MRhn
transgene insertion M, Rene Hen 		Driver: Arc
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: ArcCreERT2
Molecular description: Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-429N15) containing the entire mouse activity regulated cytoskeletal-associated protein (Arc) gene. A CreERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand-binding domain), followed by an SV40 polyadenylation sequence, was inserted into the translation initiation site of the gene. Founder lines M and F were established and maintained.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Arc-cre/ERT2)MRhn activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 10 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory