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Tg(LTF-EGFP/cre/PGR)15Klin - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(LTF-EGFP/cre/PGR)15Klin
transgene insertion 15, Kurt Lin 		Driver: LTF
Type: Transgenic (Inducible, Recombinase, Reporter)
Inducer: mifepristone
Synonym: Lf-GCrePR1e, Tg(LTF-EGFP/Cre/PR1e)15Klin
Molecular description: A construct was generated with a triple-fusion sequence EGFP/cre/PGR (encoding EGFP, cre recombinase, and the human progesterone ligand binding domain - aa F642-L901 of LBD). The fusion gene was cloned downstream of the human lactoferrin promoter (LTF). The LfB-GCrePR1e construct was used for microinjection and 12 founders were obtained. Four founders (#'s 7, 11, 15, and 27) were crossed to R26-lacZ reporter mice. Line 15 was used to generate most of the results in the original study.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(LTF-EGFP/cre/PGR)15Klin activity also observed in:
hemolymphoid system, integumental system, reproductive system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:209793 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory