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Tg(Hmx3-icre)1Kess - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Hmx3-icre)1Kess
transgene insertion 1, Nicoletta Kessaris 		Driver: Hmx3
Type: Transgenic (Recombinase)
Synonym: Nkx5-1-Cre
Molecular description: The transgene construct was generated by fusing the codon-improved cre recombinase (icre) sequence with a nuclear localization signal, to the translation initiation codon of the Hmx3 (Nkx5-1) gene located in a bacterial artificial chromosome (BAC). An SV40 polyadenylation signal followed the cre sequence. This modified BAC was used to generated transgenic mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hmx3-icre)1Kess activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:151793 Fig. 4 J:151793 Fig. 5 J:151793 Fig. 6 J:151793 Fig. 7 J:151793 Fig. S2 J:151793 Fig. S3 J:151793 Fig. S4 J:151793 Fig. S5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory