Tg(Hcn4-cre/ERT2)1Yzhao - Renal & Urinary System Recombinase Activity Detail MGI Mouse

Tg(Hcn4-cre/ERT2)1Yzhao - Renal & Urinary System
Recombinase Activity Detail

Allele Information | Images | Recombinase Activity | References

Allele Information

Allele:

Tg(Hcn4-cre/ERT2)1Yzhao
transgene insertion 1, Yong Zhao

Driver: Hcn4
Type: Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Hcn4-CreERT2

Molecular description:

Recombineering methods were used to insert a cre/ERT2 cassette immediately after the ATG start codon of the Hcn4 locus in a bacterial artificial chromosome (this BAC does not encode other proteins or micro RNAs). The BAC construct was purified and used for pronuclear injection of fertilized oocytes. Two founders were generated, with essentially identical cre activity patterns following tamoxifen treatment being observed. One line was chosen for detailed analyses.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Tg(Hcn4-cre/ERT2)1Yzhao activity also observed in:
cardiovascular system, respiratory system

Images

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J:207828 Fig. S3

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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