Kit<tm1(cre/ERT2)Dsa> - Cardiovascular System Recombinase Activity Detail MGI Mouse

Kit^{tm1(cre/ERT2)Dsa} - Cardiovascular System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Kit^{tm1(cre/ERT2)Dsa}
KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Dieter Saur

Driver: Kit
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

c-Kit^CreERT2

Molecular description:

A targeting construct with an Frt-flanked neo selection cassette 3' of the cre/ERT2 sequence was used for homologous recombination in ES cells. Cre recombinase was inserted into the ATG site in exon 1 of the Kit locus. Germline transmission of the allele was achieved by crossing to C57BL/J mice.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Kit^{tm1(cre/ERT2)Dsa} activity also observed in:
extraembryonic component, head, hemolymphoid system, sensory organs, skeletal system

Tissue Information

Cardiovascular System

Other recombinase alleles with activity in Cardiovascular System tissues:

A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Aldh1l1^{em1(cre/ERT2)Nju}, Alpl^tm1(cre)Nagy ...(more)

Images

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J:228184 Fig. 5

J:228184 Fig. S7

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

32 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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