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Tg(Kcne1-cre/ERT2)1Imos - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Kcne1-cre/ERT2)1Imos
transgene insertion 1, Ivan P Moskowitz 		Driver: Kcne1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: minK:CreERT2
Molecular description: The transgene construct was generated by BAC recombineering methods in bacteria. The Kcne1 (minK) coding sequence in BAC RP23276-120 was replaced with a cre/ERT2-bGH pA-Frt-Zeo-Frt cassette. The purified BAC was microinjected into fertilized CD-1 oocytes. Four founder lines that exhibited consisted inducible cre activity in the cardiac conduction were obtained. One line was analyzed in greater detail. Line numbers are not available.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Kcne1-cre/ERT2)1Imos activity also observed in:
muscle
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:178662 Fig. 2 J:178662 Fig. 3 J:178662 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory