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Nkx3-2tm3.1(cre)Tlu - Skeletal System
Recombinase Activity Detail
Allele Information
NK3 homeobox 2; targeted mutation 3.1, Thomas Lufkin
Driver: Nkx3-2
Type: Targeted (Recombinase)
Synonym: Bapx1ICIE
Molecular description: A targeting vector was generated by inserting an IRES-cre-IRES-EGFP-Frt-PGK-gb2-Neo-Frt cassette into the 3'UTR of the Nkx3-2 gene sequence in a BAC (RP24-148P5), The 20.6 kb BAC targeting vector was electroporated into V6.4 ES cells for homologous recombination. The neo cassette was subsequently removed by FLPe-mediated recombination.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Nkx3-2tm3.1(cre)Tlu activity also observed in:
alimentary system, branchial arches, limbs, mesenchyme
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
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J:178893 Fig. 2A J:178893 Fig. 3 J:178893 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory