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Tg(BEST1-cre)1Jdun - Sensory Organs
Recombinase Activity Detail
Allele Information
Allele:
Tg(BEST1-cre)1Jdun
transgene insertion 1, Joshua L Dunaief
Driver: BEST1
Type: Transgenic (Recombinase)
Synonym: BEST1-cre
Molecular description: A fragment of the human BEST1 promoter (nucleotides -585 to +38) drives cre recombinase cDNA, the SV40 t-antigen intron, and HSV-TK polyA in the construct. This was purified and microinjected into C57BL/6 zygotes. Six founders were generated with one F2 line that showed the highest percentage of cre immunoreactivity in the RPE was selected for further study. (Expression of cre was mosaic, with 50-90% of RPE cells being labeled.) This line has a transgene copy number of 20 determined by qPCR analysis.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Sensory Organs Other recombinase alleles with activity in Sensory Organs tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory