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Tg(Atp4b-cre)3Xya - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Atp4b-cre)3Xya
transgene insertion 3, Xiao Yang 		Driver: Atp4b
Type: Transgenic (Recombinase)
Synonym: Atp4b-Cre
Molecular description: The 1.0 kb promoter of the Atp4b gene was cloned into a vector upstream of the 1.2 kb cre recombinase coding sequence and a 2.1 kb human growth hormone gene polyadenylation signal. The 4.3 kb construct was linearized and injected into pronuclei of fertilized FVB oocytes. Two founder animals (3 and 5) were obtained that had the transgene integrated into the genome. Analyses of crosses to a reporter line showed cre recombination occurred only in the stomach, detected at P13. Both lines showed the same pattern of recombination.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory