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Tg(Adipoq-cre)#Pesch - Adipose Tissue
Recombinase Activity Detail
Allele Information
Allele:
Tg(Adipoq-cre)#Pesch
transgene insertion, Philipp E Scherer 		Driver: Adipoq
Type: Transgenic (Recombinase)
Synonym: 5.4-kb Cre
Molecular description: A 5.4-kb promoter construct containing a 4.9-kb upstream adiponectin promoter sequence, the first exon, 200 bp from the 5' end of intron 1, 200 bp from the 3' end of intron 1, and a partial fragment of the second exon was generated. The endogenous ATG in the exon 2 fragment was mutated to ATA to facilitate correct translation initiation of the transgene. The construct was fused to the cre recombinase open reading frame and the linearized fragment was microinjected into FVB pronuclei. Founders were backcrossed to FVB mice. No line numbers were specified.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Adipose Tissue Other recombinase alleles with activity in Adipose Tissue tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory