|
|
|
Allele Information
|
|
Allele:
|
Sox17tm2.1(icre)Heli
SRY-box containing gene 17;
targeted mutation 2.1, Heiko Lickert
|
Driver: Sox17
Type: Targeted (knock-in)
|
|
|
Synonym:
|
Sox172A-iCre, Sox17-2A-iCre, Sox172A-iCredeltaneo, Sox17tm2.1(icre)Lic, Sox17- 2Aicre
|
|
Molecular description:
|
The Sox17 translational stop codon in exon 5 was replaced by a T2A (Thosea asigna virus, TaV) self-cleaving peptide followed by the improved Cre (iCre) for the efficient and equimolar translation of Sox17 and icre. Sox17 and icre are postranslationally cleaved by a 2A-mediated ribosome-skipping mechanism. The FRT-flanked neo selection cassette was subsequently deleted in the germline by FLP-mediated recombination.
|
|
Find mice (IMSR):
|
Mouse Strains:
0 lines available
Cell Lines:
0 lines available
|
|
Additional Tissues:
|
Sox17tm2.1(icre)Heli activity also observed in:
|
|
|
Tissue Information
|
|
Head
|
Other recombinase alleles with activity in Head tissues:
Dcttm1(cre)Bee,
Foxg1tm1(cre)Skm,
HhatTg(TFAP2A-cre)1Will,
Hoxb1tm1(cre)Og,
Mapttm1(cre)Nagy,
Myf5tm3(cre)Sor,
Myod1tm2.1(icre)Glh,
Osr2tm2(cre)Jian,
Sox17tm1(icre)Heli,
Ssttm2.1(cre)Zjh,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Camk2a-cre)1Nobs,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CMV-cre)1And,
Tg(Col10a1-cre)1427Vdm,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Csrp1-cre)1Sjc,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Dhh-cre)1Mejr,
Tg(Dmp1-cre)1Jqfe,
Tg(EIIa-cre)C5379Lmgd,
Tgfb3tm1(cre)Vk,
Tg(Frzb-cre)1Tylz,
Tg(Frzb-cre)2Tylz,
Tg(Frzb-cre)3Tylz,
Tg(Gabra6-cre)B1Lfr,
Tg(Ghrhr-cre)3242Lsk,
Tg(mI56i-cre)6-2Clou,
Tg(Mpz-cre)94Imeg,
Tg(Nes-cre)1Atp,
Tg(Osr1-cre)4Mrt,
Tg(P0-Cre)3Gth,
Tg(Pax6-cre)1Zkoz,
Tg(Pcp2-cre)1Amc,
Tg(POU3F4-cre)M51Cren,
Tg(Pres-cre)1Jnz,
Tg(Runx2-icre)1Jtuc,
Tg(Smad7-cre)1Sjc,
Tg(Tagln-cre)1Jomm,
Tg(Tie1-cre)9Ref,
Tg(TSPY-cre)33aYfcl,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre)3Gfk,
Tg(Tyrp1-cre)1Ipc,
Tg(Zp3-cre)3Mrt
(less)
|
|
|
Images
|
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail.
Reset Images
J:155991
Fig. 2
|
|
Recombinase Activity
|
Click heading to resort table.
|
|
References
|
|
Analysis Tools