About   Help   FAQ
Tg(Pomc-cre)5Brn - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pomc-cre)5Brn
transgene insertion 5, Anton Berns 		Driver: Pomc
Type: Transgenic (Recombinase)
Synonym: Tg(Pomc1-cre)1Brn, Tg(Pomc-cre)1Brn, Tg(PomcCre)5Brn
Molecular description: This transgene contains 706 base pairs of 5' flanking sequence containing the promoter of the rat pro-opiomelanocortin gene followed by the coding sequence for Cre recombinase with an amino-terminal nuclear localization signal (nlsCre), a synthetic intron, and SV40 splice and polyadenylation signals. Progeny of mice bearing this transgene crossed to lacZ Cre reporter mice exhibited large numbers of X-gal staining cells in the intermediate lobe and lesser staining in the anterior lobe of the pituitary gland.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pomc-cre)5Brn activity also observed in:
head, nervous system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:80158 Fig. 7
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory