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Tg(Pomc-cre)1Lowl - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pomc-cre)1Lowl
transgene insertion 1, Bradford B Lowell
Driver: Pomc
Type: Transgenic (Recombinase)
Synonym: Pomc-cre, Pomc-Cre(BAC2), Tg(Pomc-cre)1Stl
Molecular description: A Pomc (pro-opiomelanocortin-alpha) (bacterial artificial chromosome; RPCI22-372J15) was used to generate mice expressing cre under the control of the Pomc promoter. The cre recombinase cDNA was inserted via homologous recombination into the first ATG transcription start site, ablating the first 30bp of the POMC coding sequence. This transgenic vector was introduced to FVB-derived embryos.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pomc-cre)1Lowl activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 67 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory