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Tg(Ppp1r1b-cre)1Meeh - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ppp1r1b-cre)1Meeh
transgene insertion 1, Michelle E Ehrlich 		Driver: Ppp1r1b
Type: Transgenic (Recombinase)
Synonym: A11K20IRESCre, D32-Cre, D9-Cre, DARPP-32Cre
Molecular description: An IRES-cre fragment with a nuclear localization signal sequence (nls) and an SV40 polyA sequence was inserted into a plasmid containing genomic fragments of Ppp1rb1 from 3 clones. The transgenic construct was injected into fertilized C57BL/6 oocytes. Two potential founders were obtained but only one founder was successfully bred to generate the line. Insertion of a single copy of the transgene was verified by Southern blot.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ppp1r1b-cre)1Meeh activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:127863 Fig. 2 J:127863 Fig. 3 J:127863 Fig. 4 J:127863 Fig. 5 J:127863 Fig. 6 J:151962 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory