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Tg(Lhx6-icre)1Kess - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Lhx6-icre)1Kess
transgene insertion 1, Nicoletta Kessaris 		Driver: Lhx6
Type: Transgenic (Recombinase)
Synonym: Lhx6Cre, Lhx6-Cre, Tg(Lhx6-cre)1Kess
Molecular description: Homologous recombination in bacteria was used to modify a 235Kb BAC RP24-384G1 containing 137 Kb upstream and 80 Kb downstream of the Lhx6 gene. An icre (improved cre) coding sequence was fused to the ATG of Lhx6 in exon 1 using a PCR-based approach. An SV40 polyA was inserted downstream of iCre. The construct was designed to delete the coding sequence of exon 1, as well as the first 80 bp from the first intron. Mice were generated by pronuclear injection of the construct into fertilized oocytes. No line number is given.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Lhx6-icre)1Kess activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:151793 Fig. S6 J:164291 Fig. 7 J:330767 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 49 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory