Et(cre/ERT2)4Rdav - Head Recombinase Activity Detail MGI Mouse

Et(cre/ERT2)4Rdav - Head
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Et(cre/ERT2)4Rdav
enhancer trap 4, Ron Davis

Driver: Et(cre/ERT2)4Rdav
Type: Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Molecular description:

An enhancer trap transgenic approach was used to generate these mice. The TK-bgi-cre:ERT2-bGHpA transgene was designed with the thymidine kinase (TK) minimal promoter driving a cre-ER^T2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 4 was established on a C57BL/6J genetic background.

Collection:

Neuroscience Blueprint cre

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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