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Lmx1btm2(cre/ERT2)Rjo - Limbs
Recombinase Activity Detail
Allele Information
LIM homeobox transcription factor 1 beta; targeted mutation 2, Randy L Johnson
Driver: Lmx1b
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Lmx1b-IREScreERT2
Molecular description: An IREScreERT2 cassette followed by a loxP flanked PGK-neo cassette was inserted into the 3'UTR of the Lmx1b locus by homologous recombination in PC3 ES cells. Cre mediated recombination subsequently removed the PGK-neo cassette upon transmission from male chimeric mice. The protamine-cre transgene contributed by the PC3 cells was separated from the knock-in allele by crossing germline male mutants with C57BL/6 mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
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J:149241 Fig. 3 J:149241 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory