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Hprttm14(Ple103-EGFP/cre)Ems - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Hprttm14(Ple103-EGFP/cre)Ems
hypoxanthine guanine phosphoribosyl transferase; targeted mutation 14, Elizabeth M Simpson
Driver: HAP1
Type: Targeted (knock-in)
Synonym: HAP1-EGFP/cre, Hprt1tm14(mEMS675)Ems, Hprt1tm14(Ple103-EGFPcre;mEMS675)Ems, Ple103
Molecular description: The Ple103-EGFP/cre transgene (pEMS1083) was designed with the 877 bp Ple103 minipromoter (HAP1-A; derived from a segment of the basal promoter element of the human huntingtin-associated protein 1 (HAP1) gene) upstream of a minimal F5 mutant-frt site, an EGFP/Cre fusion protein (enhanced green fluorescent protein (with mutated stop) and Cre recombinase), a nuclear localization signal, a second minimal frt site, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2). This construct was targeted as a single copy knockin to the Hprtsb-m3 mutant locus on the X chromosome.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 4 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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J:164356 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory