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Slc1a3tm1(cre/ERT2)Mgoe - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Slc1a3tm1(cre/ERT2)Mgoe
solute carrier family 1 (glial high affinity glutamate transporter), member 3; targeted mutation 1, Magdalena Goetz 		Driver: Slc1a3
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: GLAST-CreER, GLAST::CreERT2, GLAST::CreERT2/ZEG, Slc1a3tm1(cre/ERT2)Mgo
Molecular description: A cre/ERT2 cassette was inserted, along with an Frt flanked PGK-neomycin selection cassette, into the EcoRI site in exon 2 66 bp upstream of the translation initiation site. Heterozygous mice were later crossed with Tg(ACTFLPe)9205Dym mice to excise the neomycin selection cassette.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Slc1a3tm1(cre/ERT2)Mgoe activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:161345 Fig. 1 J:161345 Fig. 2 J:161345 Fig. 3 J:161345 Fig. S1 J:161345 Fig. S2 J:161345 Fig. S3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 92 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory