Tg(Myh11-icre/ERT2)1Soff - Integumental System Recombinase Activity Detail MGI Mouse

Tg(Myh11-icre/ERT2)1Soff - Integumental System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Tg(Myh11-icre/ERT2)1Soff
transgene insertion 1, Stefan Offermanns

Driver: Myh11
Type: Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Myh11-CreER^T2-Off, SMCCre, SMMHC-CreER^T2, Tg(Myh11-cre/ERT2)1Soff, Tg(Myh11-cre/ESR1)1Soff

Molecular description:

The mouse promoter from BAC clone 26630 was used to drive inducible icre expression in smooth muscle cells. An frt-flanked beta-lactamase gene contained within the cre/ESR1 cassette was removed by flp mediated recombination prior to micro-injection into fertilized oocytes. No line information was given.

Find mice (IMSR):

Mouse Strains: 2 strains available Cell Lines: 0 lines available

Additional Tissues:

Tg(Myh11-icre/ERT2)1Soff activity also observed in:

adipose tissue, alimentary system, cardiovascular system, hemolymphoid system ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

246 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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