About   Help   FAQ
Tg(Nes-cre/ERT2)4Imayo - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nes-cre/ERT2)4Imayo
transgene insertion 4, Itaru Imayoshi 		Driver: Nes
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Nes-CreERT2, Nestin-CreERT2line4, Tg(Nes-cre/ERT2)4Kag
Molecular description: This transgene consists of a 5.8 kb fragment of the rat Nes promoter and a 1.8 kb fragment of the second intron of Nes driving expression of a tamoxifen-inducible form of cre recombinase followed by an SV40 poly A sequence. Three lines were created (lines 1, 4, and 5-1) with differing levels of activity (high, medium, and low, respectively) and leakiness (high, low and none, respectively).
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nes-cre/ERT2)4Imayo activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:110145 Fig. 2
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 24 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory