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Allele Information
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Allele:
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Tg(Tek-cre)2352Rwng
transgene insertion 2352, Rong Wang
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Driver: Tek
Type: Transgenic
(Recombinase)
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Synonym:
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Tg(Tek-cre)1Lfr, Tg(Tie2-Cre)2352, tie2-cre, Tie2Cre
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Molecular description:
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A transgenic construct containing sequence encoding cre under the control of of the mouse Tek, endothelial-specific receptor tyrosine kinase (also known as Tie2), promoter was introduced into FVB/N donor eggs. Founder line 2352 was subsequently established. Cre recombinase expression is detected in most endothelial cells and blood islands of the extraembryonic mesoderm by embryonic day (E)7.5, in the dorsal aorta by E8.5 and is very strong in head vasculature by E9.
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Find mice (IMSR):
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Mouse Strains:
2
strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Tek-cre)2352Rwng activity also observed in:
cardiovascular system,
hemolymphoid system,
mesenchyme
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Tissue Information
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Extraembryonic Component
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Other recombinase alleles with activity in Extraembryonic Component tissues:
Alpltm1(cre)Nagy,
Cdh5em1(cre/ERT2)Smoc,
Commd10Tg(Vav1-icre)A2Kio,
Edil3Tg(Sox2-cre)1Amc,
Elf5em1(cre)Jilu,
Eomestm4.1(icre)Rob,
Esrrbtm1(cre)Yba,
Fgf18tm2.2(cre/ERT2)Dor,
Foxa2tm2.1(cre/Esr1*)Moon,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Hlfem2(cre/ERT2)Suda,
Hnf4atm1(cre)Sdv,
Hoxa13tm1.1(cre)Mlkn,
Hoxa13tm1(cre)Mlkn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Kdrtm1(cre)Sato,
Kittm1(cre/ERT2)Dsa,
Krt19tm1(cre)Mmt,
Mapttm1(cre)Nagy,
Mecomem1(cre/ERT2)Suda,
Meox2tm1(cre)Sor,
Mesp1tm2(cre)Ysa,
Nfatc1em4(cre/ERT2)Bzsh,
Nkx1-2tm2296.1(cre/ERT2)Arte,
Nkx2-5tm2(cre)Rph,
Notch1tm3(cre)Rko,
Prdm1tm3(icre)Rob,
Prl2c2tm1(cre)Gle,
Runx1tm1(cre/Esr1*)Ims,
Runx1tm2.1(cre/Esr1*)Ims,
Shhtm2(cre/ERT2)Cjt,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Sox17tm4.1(icre/ERT2)Heli,
Ssttm2.1(cre)Zjh,
Synbem1(cre)Mdf,
Taglntm2(cre)Yec,
Tg(ACTA1-cre)79Jme,
Tg(Acvrl1-cre)L1Spo,
Tg(Cdh5-cre)1Spe,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cdx1-cre)23Kem,
Tg(Csf1r-cre/Esr1*)1Jwp,
Tg(Cyp19a1-cre)5912Gle,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Etv2-cre)15508Djg,
Tg(Etv2-cre)#Blk,
Tg(Fabp4-cre)1Rev,
Tg(Foxa3-cre)1Khk,
Tg(Gata1-cre)1Sho,
Tg(Gcm1-cre)1Chrn,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hoxb6-cre)A5Mku,
Tg(Hoxb6-cre)C33Mku,
Tg(Hoxb6-cre)#Mku,
Tg(Hspa2-cre)1Eddy,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Kdr-cre)15962Brei,
Tg(Leftb-cre)1Hmd,
Tg(Lefty1-cre/ERT2)8Hmd,
Tg(Nes-cre)1Atp,
Tg(Nrp2-cre,-EGFP)#Qsch,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Prrx1-cre)1Cjt,
Tg(Sim1-cre)1Lowl,
Tg(Smarcd3-cre/ERT2)#Bbr,
Tg(Sox2-flpo)#Mhem,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jomm,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(T-cre)1Lwd,
Tg(Tek-cre)1Ywa,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Tlx2-cre)#Ymor,
Tg(Tpbpa-cre,-EGFP)5Jcc,
Tg(Ttr-cre)1Hadj,
Tg(Vav1-cre)8Cgp,
Tg(Vil1-cre)20Syr,
Tg(Wnt11-cre/ERT2)1Jwng,
Twist2tm1.1(cre)Dor
(less)
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Images
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J:104401
Fig. 1
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Recombinase Activity
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References
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Analysis Tools