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Tg(Ascl1-EGFP,-cre)1Jejo - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ascl1-EGFP,-cre)1Jejo
transgene insertion 1, Jane Johnson 		Driver: Ascl1
Type: Transgenic (Recombinase)
Synonym: Ascl1-GIC, M1-GIC, Tg(RPCI-428P21-EGFP,-cre)1Jejo
Molecular description: The transgene is a bacterial artificial chromosome (BAC), RPCI-428P2, bearing a 305 kb mouse genomic segment that contains the Ascl1 locus(98 kb of 5' and 206 kb of 3' of the start codon), in which the coding sequence of the gene has been replaced with an EGFP-IRES-CRE cassette. The GFP reporter expression is low but reflects the Ascl1 pattern throughout multiple stages and in multiple regions, including the caudal neural tube, the telencephalon and diencephalon, and sympathetic and enteric nervous systems.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ascl1-EGFP,-cre)1Jejo activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:117032 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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04/16/2024
MGI 6.23 		The Jackson Laboratory