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Ctsktm1(cre)Ska - Skeletal System
Recombinase Activity Detail
Allele Information
cathepsin K; targeted mutation 1, Shigeaki Kato
Driver: Ctsk
Type: Targeted (Null/knockout, Recombinase)
Synonym: Cathepsin K-Cre, CtskCre, CtsKCre
Molecular description: A cre recombinase gene and a downstream frt-flanked kanamycin/neomycin resistance gene was inserted into the endogenous ATG start site of the gene, replacing the first four exons. Chimeric mice were crossed with a deleter strain to remove the selection cassette. Cre expression in heterozygotes was detected in mature osteoclasts but not osteoblasts when crossed with a tester strain.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Ctsktm1(cre)Ska activity also observed in:
reproductive system
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory