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Tg(Mylpf-cre)3Kraj - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Mylpf-cre)3Kraj
transgene insertion 3, Stan Krajewski 		Driver: Myl11
Type: Transgenic (Recombinase)
Synonym: CRE3, MLC2v-CRE3, MLCcre
Molecular description: A 250-bp fragment of the rat ventricular light chain II gene (Mylpf) was used as promoter to drive expression of the cre recombinase cDNA. Crosses of these mice were made to mice (dh4) carrying a transgenic reporter gene (a dominant-hygR gene separated from a constitutive PGK promoter by a loxP-flanked PGK-neo cassette; cre recombination results in generation of the active-hygR allele detected by PCR). Line 3 was determined to express cre selectively in the brain.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Mylpf-cre)3Kraj activity also observed in:
head, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:99342 Fig. 2 J:99342 Fig. 3.1 J:99342 Fig. 3.2 J:99342 Fig. 3.3 J:99342 Fig. 3.4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory