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Tbx1tm6(cre)Bld - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tbx1tm6(cre)Bld
T-box 1; targeted mutation 6, Antonio Baldini 		Driver: Tbx1
Type: Targeted (Recombinase)
Synonym: Tbx1Cre
Molecular description: An IRES-cre cassette was inserted into exon 5. Expression of cre is induced in head mesoderm and mesoderm located dorsally to the cardiac cresent at E75. to E8.5, most mesoderm dorsal and lateral to the pharynx and head mesoderm at 4- and 6-somite stage, and mesoderm that virtually surrounds the pharynx at 8-somite stage in a pattern that is similar to Tbx1 expression. Author states that this is a null allele.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tbx1tm6(cre)Bld activity also observed in:
muscle
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:220957 Fig. 8
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 24 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory