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Tg(Ddx4-cre)1Dcas - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ddx4-cre)1Dcas
transgene insertion 1, Diego H Castrillon
Driver: Ddx4
Type: Transgenic (Recombinase)
Synonym: Mvh-Cre, Vasa-Cre
Molecular description: A 5.6kb fragment of the Ddx4 promoter was ligated to the cre open reading frame with an engineered nuclear localization signal. Eight transgenic lines were created but only two possessed expressing in the gonads as early as E15. When the cre transgene is maternally expressed, all progeny can show ubiquitous recombination even if the cre is not inherited, likely due to perdurance of cre protein in the egg.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ddx4-cre)1Dcas activity also observed in:
embryo-other, sensory organs
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:125051 Fig. 3 J:125051 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory