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Tg(Cyp11a1-cre)16Mchu - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cyp11a1-cre)16Mchu
transgene insertion 16, Meng-Chun Hu 		Driver: Cyp11a1
Type: Transgenic (Recombinase)
Synonym: SCC-iCre
Molecular description: This transgene uses the cytochrome P450, family 11, subfamily a, polypeptide 1 promoter to drive expression of the codon-improved cre recombinase (iCre) in the adrenal cortex and gonads, as well as the diencephalons and midbrain. Two copies of the HS4 insulator sequences derived from chicken beta-globin LCR were inserted into the cassette either upstream or downstream of the construct in reverse direction. Lines 30 and 41 were also made and expressed at a similar high level and in a consistent pattern.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cyp11a1-cre)16Mchu activity also observed in:
endocrine system, head, nervous system
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:121826 Fig. 2 J:121826 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory