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Ighg1tm1(cre)Cgn - Hemolymphoid System
Recombinase Activity Detail
Allele Information
Allele:
Ighg1tm1(cre)Cgn
immunoglobulin heavy constant gamma 1 (G1m marker); targeted mutation 1, University of Cologne
Driver: Ighg1
Type: Targeted (Recombinase)
Synonym: Cgamma1-cre, Cy1-cre, IghC gamma1-cre, Ighg1tm1(IRES-cre)Cgn
Molecular description: An IRES-cre was inserted into the 3' region of the Cgamma1 locus between the last membrane-coding exon and its polyadenylation sites. This targeting design allows for the expression from the locus of a bicistronic mRNA consisting of the Cgamma1 and Cre transcript. An FRT site flanked neomycin resistance gene cassette was removed via Flp recombinase expression.
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Tissue Information
Hemolymphoid System Other recombinase alleles with activity in Hemolymphoid System tissues:
Images
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J:109583 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 91 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory