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Tg(Hand2-cre)7-1Clou - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion 7-1, David E Clouthier
Driver: Hand2
Type: Transgenic (Recombinase)
Synonym: dHAND-Cre, Hand2-Cre, Tg(Hand2-cre)#Clou
Molecular description: A 7.4 kb of the Hand2 upstream region, containing the pharyngeal arch and cardiac enhancer elements, was fused to Cre cDNA containing a nuclear localization signal (NLS) and SV40-pA. Two lines were created (7-1 and 7-2), with expression of line 7-2 being less intense than that of line 7-1.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hand2-cre)7-1Clou activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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J:83364 Fig. 2 J:83364 Fig. 4 J:83364 Fig. 5
Reprinted with permission from Elsevier from 10.1016/S0012-1606(03)00068-X Dev Biol 257: 263-77, Ruest LB; Dager M; Yanagisawa H; Charite J; Hammer RE; Olson EN; Yanagisawa M; Clouthier DE, Dhand-cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Copyright 2003

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Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory