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Tg(Neurog3-cre)C1Able - Endocrine System
Recombinase Activity Detail
Allele Information
transgene insertion C1, Andrew B Leiter
Driver: Neurog3
Type: Transgenic (Recombinase)
Synonym: Neurog3(cre), Neurog3Cre, ngn3-Cre, Tg(Neurog3-cre)#Able
Molecular description: The Cre recombinase coding sequence, flanked by a nuclear localization signal and an SV40 polyadenylation site, was inserted just after the translation start site of the neurogenin 3 gene present in mouse BAC RP23-121F10, which also includes approximately 81 kb of 5' and 102 kb of 3' flanking DNA. Immunohistochemical analysis shows the same expression pattern for cre as for neurogenin 3 in adult and embryonic mice bearing this transgene. Cre recombinase activity is seen in cell types of pancreas, stomach, small intestine and colon that express or are descended from cells that express neurogenin 3 during development.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurog3-cre)C1Able activity also observed in:
alimentary system, embryo-other, hemolymphoid system, nervous system, renal and urinary system, reproductive system
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 40 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory