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Tg(Pax2-cre)1Akg - Sensory Organs
Recombinase Activity Detail
Allele Information
transgene insertion 1, Andrew K Groves
Driver: Pax2
Type: Transgenic (Recombinase)
Synonym: Pax2-Cre
Molecular description: A 121kb segment of the Pax2 gene which included 101 kb of sequence upstream of exon1, all of exons 1 and 2, part of exon 3, as well as introns 1 and 2, was modified by the insertion of IRES-cre into exon 2. Cre expression was demonstrated in the otic placode starting at the 6-7 somite stage. Cre expression also occurred in the midbrain-hindbrain boundary and the embryonic kidney. Two founders showed germline transmission of cre, and the line that displayed stronger cre mRNA expression was designated by MGI as line 1.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pax2-cre)1Akg activity also observed in:
nervous system, renal and urinary system
Tissue Information
Sensory Organs Other recombinase alleles with activity in Sensory Organs tissues:
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J:89784 Fig. 3 J:89784 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 54 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory