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Tg(Nefh-cre)12Kul - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nefh-cre)12Kul
transgene insertion 12, Ashok B Kulkarni 		Driver: Nefh
Type: Transgenic (Recombinase)
Synonym: Tg mNF-H-cre 12
Molecular description: An 8.5 kb promoter fragment of mouse Nefh, containing the 5' UTR and 40 bp of non-coding sequence of exon 1 ending before the start codon, was adjoined to sequence encoding cre recombinase with an SV40 nuclear localization signal. An SV40 polyadenylation signal was also included in the construct. Expression of cre recombinase is driven in neurons of the brain and spinal cord during late development (around E18.5). Line 12 is best described and is representative of the other lines.
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nefh-cre)12Kul activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 15 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory