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Tg(Col1a1-cre)1Kry - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Col1a1-cre)1Kry
transgene insertion 1, Gerard Karsenty 		Driver: Col1a1
Type: Transgenic (Recombinase)
Synonym: 2.3kb alpha1(I)-cre, alpha1(1) collagen-Cre, alpha1(I)collagen-Cre, alpha1(I)-Cre, Col1a12.3kbCre, Col1-Cre, Col2.3-Cre, Col-Cre
Molecular description: Sequence encoding cre recombinase was adjoined to 2.3 kb of the Col1a1 promoter. The endogenous Col1a1 promoter is active in osteoblasts throughout their differentiation and, accordingly, expression of cre recombinase was detected exclusively in bone. Cytogenetic mapping indicates that the transgene integrated on chromosome 14qE2-4.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Col1a1-cre)1Kry activity also observed in:
head, integumental system, limbs
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:77071 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 147 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory