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Tg(Kdr-cre)15964Brei - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Kdr-cre)15964Brei
transgene insertion 15964, George Breier 		Driver: Kdr
Type: Transgenic (Recombinase)
Synonym: flk-1-Cre
Molecular description: Sequence encoding cre recombinase was adjoined to Kdr promoter/enhancer sequence to drive expression of cre in the endothelial cells of the embyronic vascular system. The construct consisted of 939 bp of Kdr promoter sequence fused to cre sequence followed by a polyA signal and 2.3 kb of the first intron of Kdr. Cre-mediated recombination of a reporter transgene was observed in the embryonic vasculature at E13.5.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Kdr-cre)15964Brei activity also observed in:
cardiovascular system, head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:88924 Fig. 2 J:88924 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory