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Tg(Krt2-6a-cre)1Ism - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Krt2-6a-cre)1Ism
transgene insertion 1, Ian Smyth 		Driver: Krt2
Type: Transgenic (Recombinase)
Synonym:
Molecular description: The transgenic construct consisted of cDNA encoding cre recombinase adjoined to the mouse Krt2-6a promoter. Cre-mediated recombination was observed in the companion cell layer of hair follicles, a discrete cell population located between the inner and outer root sheaths. With retinoic acid treatment, the expression domain is expanded to the interfollicular basal and outer root sheath cells.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Krt2-6a-cre)1Ism activity also observed in:
alimentary system
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory