About   Help   FAQ
Tg(Neurog3-cre/Esr1*)1Dam - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Neurog3-cre/Esr1*)1Dam
transgene insertion 1, Douglas A Melton 		Driver: Neurog3
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Ngn3-Cre, Ngn3/CreERTM, Tg(Neurog3-cre/Esr1)1Dam
Molecular description: The sequence encoding a tamoxifen-inducible form of a cre recombinase/estrogen receptor fusion protein was adjoined to a 6.7 kb Neurog3 promoter fragment. The neurogenin 3 promoter drives the expression of cre recombinase in the islet cells of the pancreas.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurog3-cre/Esr1*)1Dam activity also observed in:
alimentary system, reproductive system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:76095 Fig. 5 J:76095 Fig. 6
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 18 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory