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Tg(Myh11-cre,-EGFP)2Mik - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Myh11-cre,-EGFP)2Mik
transgene insertion 2, Michael I Kotlikoff 		Driver: Myh11
Type: Transgenic (Recombinase, Reporter)
Synonym: MH, smMHC-Cre, smMHCCre/eGFP, smMHC/Cre/eGFP, smMHC-Cre-GFPtg, smMHC-Cre-IRES-eGFP, Tg(Myh11-cre/EGFP)1Mik
Molecular description: The transgene consists of a mouse Myh11 promoter, a cre recombinase gene, an internal ribosome entry site (IRES) and an enhanced GFP gene. 16 kb of mouse Myh11 promoter sequences was used to drive the bicistronic transgene expression in smooth muscle cells. The promoter has also been reported to be active in female germ cells. A low frequency of deletion events are also observed by inheritance from the male germline.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Myh11-cre,-EGFP)2Mik activity also observed in:
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 76 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory