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Tg(Prrx1-cre)1Cjt - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Prrx1-cre)1Cjt
transgene insertion 1, Clifford J Tabin
Driver: Prrx1
Type: Transgenic (Recombinase)
Synonym: Prx1cre, Prx1-cre, Prx1Cre, Prx-1 Cre, Prx-cre, Tg[Prx1-cre]1Cjt
Molecular description: This transgene expresses Cre recombinase under the control of a Prrx1 derived enhancer. This transgene is expressed in the early limb bud mesenchyme and in a subset of craniofacial mesenchyme. A germline Cre recombinase activity was observed in female, but not in male, as partially penetrant trait depending on the particular gene flanked by loxP sites.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Prrx1-cre)1Cjt activity also observed in:
branchial arches, embryo-other, mesenchyme, muscle, sensory organs
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:117064 Fig. 2 J:77872 Fig. 2 J:77872 Fig. 3 J:77872 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 158 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory