About   Help   FAQ
Plekha5Tg(AMH-cre)1Flor - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Plekha5Tg(AMH-cre)1Flor
pleckstrin homology domain containing, family A member 5; transgene insertion 1, Florian Guillou
Driver: AMH
Type: Transgenic (No functional change, Recombinase)
Synonym: AMH-Cre, Mis-Cre, Tg(AMH-cre)1Flor
Molecular description: The transgene consists of a human AMH promoter, a cre recombinase gene, and genomic sequences from MT1 to provide mRNA secondary structure stability. The gene trap inserted into intron 3. Northern blot analysis shows gonad-specific transgene expression in Sertoli cells of 6 day old male mice and granulosa cells of 16 day old female mice. RT-PCR confirmed normal endogenous gene expression. The insertion site of the original cre transgene was subsequenly identified as intron 3 of Plekha5.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Plekha5Tg(AMH-cre)1Flor activity also observed in:
alimentary system
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:334866 Fig. 2 J:81650 Fig. 3
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 127 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory