Plekha5<Tg(AMH-cre)1Flor> - Embryo-other Recombinase Activity Detail MGI Mouse

Plekha5^{Tg(AMH-cre)1Flor} - Embryo-other
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Plekha5^{Tg(AMH-cre)1Flor}
pleckstrin homology domain containing, family A member 5; transgene insertion 1, Florian Guillou

Driver: AMH
Type: Transgenic (No functional change, Recombinase)

Synonym:

AMH-Cre, Mis-Cre, Tg(AMH-cre)1Flor

Molecular description:

The transgene consists of a human AMH promoter, a cre recombinase gene, and genomic sequences from MT1 to provide mRNA secondary structure stability. The gene trap inserted into intron 3. Northern blot analysis shows gonad-specific transgene expression in Sertoli cells of 6 day old male mice and granulosa cells of 16 day old female mice. RT-PCR confirmed normal endogenous gene expression. The insertion site of the original cre transgene was subsequenly identified as intron 3 of Plekha5.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Plekha5^{Tg(AMH-cre)1Flor} activity also observed in:
alimentary system, reproductive system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

127 reference(s)

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