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Tg(KRT18-cre/ERT2)1Rgo - Liver And Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT18-cre/ERT2)1Rgo
transgene insertion 1, Robert G Oshima
Driver: KRT18
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: K18CreER, K18iresCreERT2
Molecular description: The transgenic construct encodes a tamoxifen inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand binding domain inserted into exon 7 of human KRT18. Human KRT18 regulatory sequences were used to drive transgene expression in epithelial cells.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(KRT18-cre/ERT2)1Rgo activity also observed in:
integumental system, nervous system, renal and urinary system, reproductive system
Tissue Information
Liver And Biliary System Other recombinase alleles with activity in Liver And Biliary System tissues:
Images
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J:81652 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory