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Nkx2-5tm2(cre)Rph - Cavities & Their Linings
Recombinase Activity Detail
Allele Information
Allele:
Nkx2-5tm2(cre)Rph
NK2 homeobox 5; targeted mutation 2, Richard P Harvey 		Driver: Nkx2-5
Type: Targeted (No functional change, Recombinase)
Synonym: Nkx2.5-Cre, Nkx2-5IRESCre
Molecular description: Sequence encoding cre recombinase adjoined to an IRES was inserted into the 3' UTR of the endogenous locus via homologous recombination. A single frt site remained in the UTR after an frt-flanked hygromycin selection cassette was excised. A lack of observed allele complementation indicated that the inserted sequence did not significantly affect expression of the endogenous locus.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Nkx2-5tm2(cre)Rph activity also observed in:
Tissue Information
Cavities & Their Linings Other recombinase alleles with activity in Cavities & Their Linings tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 72 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory