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Tg(tetO-cre)LC1Bjd - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Tg(tetO-cre)LC1Bjd
transgene insertion LC1, Hermann Bujard
Driver: tetO
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by doxycycline
Synonym: LC-1, LC1-Cre, TgLC1, TRE-LC1
Molecular description: The transgenic construct contained a bidirectional tTA/rtTA responsive promoter derived from the human cytomegalovirus promoter IE and flanked by sequence encoding luciferase and cre recombinase. Efficient cre mediated recombination, unaffected by position effect variegation, was demonstrated in hepatocytes. Transcription of in both directions was shown to be activated by rtTA in the presence of doxycycline. Transgene insertion is on chromosome 6C1 flanked by genes coding for the vomeronasal receptors V1rc14 and V1rc15 (K.Schonig, pers. commun.)
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(tetO-cre)LC1Bjd activity also observed in:
liver and biliary system, nervous system, renal and urinary system
Tissue Information
Respiratory System Other recombinase alleles with activity in Respiratory System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory