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Tg(Vil-cre)997Gum - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Vil-cre)997Gum
transgene insertion 997, Deborah L Gumucio
Driver: Vil1
Type: Transgenic (Recombinase)
Synonym: 12.4KbVilCre, Tg(Vil-cre)997Gum, Vcre, VilCre, Vil-Cre, Villin-cre, Villin.cre, VillinCre
Molecular description: A 12.4-kb promoter fragment from the villin 1 gene drives the expression of cre recombinase. Recombination occurs in villi and crypt cells of the small and large intestines, closely patterning the endogenous gene expression. According to the corresponding author (J:78815), expression is generally continuous but a small amount of mosaicism is noted in the colon. Onset of transgene expression is at 12.5 dpc, which is delayed from the endogenous mouse Vil gene expression onset of 9.0 dpc.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Vil-cre)997Gum activity also observed in:
alimentary system, cardiovascular system, nervous system, renal and urinary system, reproductive system, respiratory system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
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J:184579 Full image
Fig. Vil Adrenal P56
J:184579 Full image
Fig. Vil Adrenal P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 173 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory