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Gt(ROSA)26Sortm1(FLP1)Dym - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Gt(ROSA)26Sortm1(FLP1)Dym
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Susan Dymecki
Driver: Gt(ROSA)26Sor
Type: Targeted (Recombinase)
Synonym: CAGGS-Flpe, flipper, FLP, FLP deleter, FLPe, FLPeR, R26Fki, ROSA26Fki, ROSA26::FLPe knock in
Molecular description: An enhanced flp cassette containing a splice acceptor site was ligated to a downstream PGK-neo cassette and inserted at the endogenous locus. Efficient frt-specific recombination in transgenic mice carrying a reporter gene was reported to reflect constituitive expression of the Gt(ROSA)26Sor from preimplantation onward.
Find mice (IMSR): Mouse Strains: 4 strains available       Cell Lines: 0 lines available
Additional Tissues: Gt(ROSA)26Sortm1(FLP1)Dym activity also observed in:
embryo-other, mesenchyme, muscle, nervous system, reproductive system
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:147304 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 293 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory