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Gt(ROSA)26Sortm1(FLP1)Dym - Mesenchyme
Recombinase Activity Detail
Allele Information
Allele:
Gt(ROSA)26Sortm1(FLP1)Dym
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Susan Dymecki 		Driver: Gt(ROSA)26Sor
Type: Targeted (Recombinase)
Synonym: CAGGS-Flpe, flipper, FLP, FLP deleter, FLPe, FLPeR, R26Fki, R26FLPe, ROSA26Fki, ROSA26::FLPe knock in
Molecular description: An enhanced flp cassette containing a splice acceptor site was ligated to a downstream PGK-neo cassette and inserted at the endogenous locus. Efficient frt-specific recombination in transgenic mice carrying a reporter gene was reported to reflect constituitive expression of the Gt(ROSA)26Sor from preimplantation onward.
Find mice (IMSR): Mouse Strains: 5 strains available       Cell Lines: 0 lines available
Additional Tissues: Gt(ROSA)26Sortm1(FLP1)Dym activity also observed in:
embryo-other, head, limbs, muscle, nervous system, reproductive system
Tissue Information
Mesenchyme Other recombinase alleles with activity in Mesenchyme tissues:
Images
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J:147304 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 801 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory