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Tg(Hsp70-1-cre)6Arge - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Hsp70-1-cre)6Arge
transgene insertion 6, Argiris Efstratiadis 		Driver: Hspa1b
Type: Transgenic (Recombinase)
Synonym: Hs-cre6, Hspa1b-cre6
Molecular description: A sequence fragment from the murine Hsp70-1 locus encompassing 655 bp of the 5' flanking and noncoding sequence was adjoined to sequence encoding cre recombinase. A single integration of the transgenic construct was identified in the founder line. Graded expression of the transgenic construct (determined by a range of 0% to 100% recombination of reporter loci) was observed in non heat shock induced embryos. Additionally, heat shock induces expression.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hsp70-1-cre)6Arge activity also observed in:
renal & urinary system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:60711 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory